Abstract

Recently the synthesis of [3-13C]-, [4-13C]-, and [11-13C]- porphobilinogen, [15N,13C4]-1H - pyrrole-2,3,5 - tricar - boxylic acid, [1-15N]-3-cyano-4-methyl-1H-pyrrole and [2-13C]- and [3-13C]-cyano-4- methyl-3-pyrrolin-2-one have been published. Incorporation of 13C and 15N in these systems at any position and combination of positions has become accessible. Also mild alkylations of active methylene compounds with α-halo carbonyl compounds open up many 3-pyrrolin-2- ones and pyrrole systems based on stable isotope building blocks that have been published. This gives the access to a whole new library of stable isotope enriched pyrroles in any stable isotope enriched form. This is also the case for biliverdin IXα which after enzymatic treatment has been

How to Cite
PRATIVA B. S. DAWADI , JOHAN LUGTENBURG, Dr.. Synthesis of Biologically Important Pyrrole Derivatives in any 13C and 15N Isotope Enriched Form. Global Journal of Science Frontier Research, [S.l.], v. 12, n. 2-B, feb. 2012. ISSN 2249-4626. Available at: <https://journalofscience.org/index.php/GJSFR/article/view/414>. Date accessed: 21 may 2019.