The study investigated the nutritional compositions of leaves of Spilanthes filicualis and the in-vitro antioxidants properties of its ethanol leaf extract. The results of the proximate composition revealed the high value of carbohydrate (64.9%). Mineral and vitamin analysis showed high concentrations of calcium (20.9 mg/kg) and vitamin A (238.73 mg/100g). Qualitative and quantitative phytochemical studies of the ethanol leaf extract detected the presences of phenols, tannins, flavonoids, alkaloid, and steroids. As well as high levels of rutin (27.6μg/ ml ) and kaempferol (26. 0μg/ml). The results of the in-vitro antioxidant study of the extract showed free radical scavenging activities with highest activities at 10mg/ml against 1, 1-diphenyl -2- picrylhydrazyl, lipid peroxidation and reducing power.