Abstract

Investigations have been carried out to examine the presence of liver glycogen in normal control, diabetic control and extract treated albino rats. Estimation of liver glycogen was carried out by taking liver samples from normal control, diabetic control and extract treated albino rats. The rats weighing 150-190gm were administered intraperitonealy with 180mg/kg body weight dose of alloxan monohydrate for the induction of diabetes, with alcoholic leaf extract of Tinospora cordifolia with a oral dose of 20 ml/kg body weight from day 2 to 30 half an hour prior to feeding twice a day. It produces significant decrease in liver glycogen level.