Abstract

This study was undertaken to investigate the antifungal activities of aqueous and ethanol extracts of Securideca longepedunculata leaves and root bark against two Aspergillus species (Aspergillus niger and Aspergillus flavus). Agar incorporation method was used for antifungal testing. The results of phytochemical screening demonstrated the presence of flavonoid, saponin, alkaloids, cardiac glycoside and saponins glycosides. Highest growth inhibition (1.16+1.15mm) at 300 mg/ml, (1.67+2.88mm) and higher increase (3.16+0.57mm) at 100 mg/ml were observed. The results showed significant effect (p<0.05) of antifungal activities. In the same study, the results however, applied that the phytochemical constituents of S. longepedunculata leaves and root bark extracts can be used as potential antimicrobial agents in the management of microbial diseases caused by pathogenic Aspergillus species which can become an alternative to chemical antibiotics.