Abstract

The neurotransmitter enzymes such as acetyl and butryl cholinesterases effects as changes are studied in human beings exposed to organophosphorous pesticides during agriculture practices of spraying in the areas of Nuziveedu Krishna district, A.P, INDIA.These changes are significant as it was found to be more than 45% in Acetyl cholinesterases (AChE) and 36% in butryl cholinesterase (BChE) decrement in the exposed group when compared to non-exposed group as controls. First absorption, by people resulting toxicity as chronic by the production of oxygen free radicals, being heterotrophic metabolically, results in the alteration of homeostasis leading to oxidative stress that culminates the non maintenance of the antioxidants continuously due to imbalance.