Novel Aspects of Domino Reaction of Indoles with Homo- Phthalaldehyde and Tere-phthalaldehyde
Keywords:
work domino reaction of indole, catalyst and solvent afford the novel
Abstract
In the present work domino reaction of indole with homophthaladehyde (1) have been investigated for the first time. The reaction have been done in presence of glacial acetic acid as catalyst and solvent afford the novel un probable mixture of two isomers A and B of benzo[7]anulene (2) that couldn’t be divided accompany with the formation of the predictable tetraindole (3) in a yield of 46 to 38 % respectively. Terephthaladehyde (4) condensed with indoles in glacial acetic acid in a molar ratio (1:4) affording compounds 5a,b in a high yield of 93 - 95 % after a short time of stirring at room temperature. Compounds 5a,b can act as nucleophile due to the unoccupied two positions of the four indole rings. Accordingly we now present for the first time a expedient method for the synthesis of the novel extensive ring systems 6 and (7a-f) via condensation reaction of compound 5a with aryl or heteroaryl substituted aldehydes in a molar ratio (1:2).
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
Published
2014-05-15
Issue
Section
License
Copyright (c) 2014 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.