Synthesis of 1-(2-(4-substitutedphenylamino)-imidazo[2,1-b] benzoxazol-3-yl) ethanone
isoxazolones; 2chlorobenzo[d]oxazole; Imidazobenzoxazol; Baseinducedrearrangements
Abstract
4 -acetyl -3-(4-substitutedphenylamino)- isoxazole - 5(2H)-one, substituted on nitrogen with a 2-chlorobenzo[d] oxazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenylamino)-imidazo-[2,1-b]-benzoxazol- 3-yl)-ethanone.
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2014-03-15
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