Synthesis, Characterization and Antimicrobial Activity of Azetidin-2-one based Phenyl Sulfonyl Pyrazoline Derivatives
chalcones, phenyl sulfonyl-pyrazolines, azetidin-2-one, antimicrobial activity
Abstract
A new series of 4-(4-Chlorophenyl)-3-chloro-1-{4-[5-(Substitutedphenyl)-1-(phenylsulfonyl)-4,5-dihydro-pyrazol-3-yl]phenyl}azetidin-2-one are synthesized by reacting 3chloro-1-{4-[5-(Substitutedphenyl)-4,5-dihydro-pyrazol-3-yl]phenyl}-4-(4-Chlorophenyl) azetidin-2-one with Benzene sulfonyl chloride in presence of pyridine. All these compounds were characterized by means of their IR, 1H NMR, Spectroscopic data and were tested for their antibacterial and antifungal activities by broth dilution method.
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2014-03-07
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