The aim of the present study is to investigate the bioactive compounds from the leaf extract of Mallotus oppositifolius using GCMS analysis. The chromatogram showed nine peaks indicating the presence of nine compounds in the extract. The major phytocompounds in the leaf were Glutaconic anhydride with the highest concentration in the extract, 40.19 peak area %, RT 22.686 and molecular formula C5H4O3; 2-Mercaptophenol with 18.23 peak area %, RT 22.068 and molecular formula C6H6 OS. Iso-Valreic and Valeric acids with 12.39,2.53 peak area %, RT 3.676,7.037 and the same molecular formula C5H10 O2 which had been proposed to have anticonvulsant effect in valerian and act as neurotransmitter. Oleamide with the least concentration of 2.15 peak area %, RT 27.959 and molecular formula C18H35NO which could induce sleep in animals, being studied as a potential medical remedy for mood and sleep disorder and cannabinoid–regulated disorder. The phytochemicals in Mallotus oppositifolius could be of therapeutic importance.

How to Cite
K. K., MADUBUIKE A.J., AMAKU F.J., CHIKA IKENGA, OTUOKERE I.E., Igwe. GC-MS Analysis for Structural Identification and Bioactive Compounds in Methanolic Leaf Extract of Mallotus oppositifolius.. Global Journal of Science Frontier Research, [S.l.], may 2016. ISSN 2249-4626. Available at: <https://journalofscience.org/index.php/GJSFR/article/view/1776>. Date accessed: 25 jan. 2022.