Dipolar 1,3-Cycloaddition:Synthesis of New Pyrazolinic Compounds Derived From Eugenol
Keywords:
dipolar 1, 3-cycloaddition; synthesis; eugenol; pyrazolinic compounds
Abstract
It is now well known that pyrazolic and pyrazolinic derivatives are a class of heterocyclic compounds with high biological activity. In our laboratory, many studies have been made on the synthesis, stereochemistry, the complexing power and biological properties of various pyrazolic and pyrazolinic structures. The new pyrazolines presented in this work were prepared by cycloaddition of 1,3-dipole (the diarylnitrilimine) on eugenol and acetyleugenol which are two natural extracted dipolarophiles from cloves. The structures of the obtained cycloadducts have been studied and confirmed on the basis of IR spectroscopic parameters, NMR-1H and 13C.
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Published
2015-03-15
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