Qualitative and Quantitative Analysis for Determination of Glue Snifferas Urine

Authors

  • Mohamad Raizul Zinalibdin

  • Abdul Rahim Yacob

  • mohdraizul

glue, hippuric acid, color test, ultra violet-visible

Abstract

Inhalant abuse is defined as an intentional inhalation of solvents or volatile substances present in materials such as glues and paints. The most commonly abused inhalant today is glue due to low price and easy access. Glue sniffing produces fast and pleasurable sensory experience to the abuser. Quantitative analysis of hippuric acid using UV-Vis at wavelength 417 nm was determined successfully. The results gave a regression coefficient of 0.994. The recovery, accuracy and coefficient variance of hippuric acid were 96.57%, 2.94% and 0.50% respectively. Reversed-phase high performance liquid chromatography using a simple method for the simultaneous determination of hippuric acid and benzoic acid was also described. The chromatography was performed on a Nova-Pak C18 (3.9 x 150 mm) column with a mobile phase of methanol: water: acetic acid (20:80:0.2) using UV detection at 254 nm. The calibration of standards was linear within concentration range of 0.125 to 6.0 mg/mL of hippuric acid and benzoic acid respectively.

How to Cite

Qualitative and Quantitative Analysis for Determination of Glue Snifferas Urine. (2014). Global Journal of Science Frontier Research, 14(15), 23-28. https://journalofscience.org/index.php/GJSFR/article/view/

Author Biographies

Mohamad Raizul Zinalibdin

Mohamad Raizul Zinalibdin is a researcher affiliated with Universiti Teknologi Malaysia and the Jabatan Kimia Malaysia, Cawangan Johor. He holds a Master of Science in Chemistry and has contributed to the field of analytical chemistry, with a particular focus on forensic science and the detection of substances such as glue solvents. His notable work includes the development of a mobile test kit for detecting hippuric acid, a glue solvent metabolite, and the qualitative and quantitative analysis for determination of glue sniffers' urine. With 14 publications, 30 citations, an h-index of 3, and an i10-index of 1, his research spans areas like food chemistry, environmental chemistry, and oil & fats. He also serves as a reviewer for the Global Journal of Science Frontier Research (GJSFR), reflecting his expertise in chemistry and related disciplines.

mohdraizul

Mohamad Raizul Zinalibdin is a researcher affiliated with Universiti Teknologi Malaysia and based at Jabatan Kimia Malaysia, Cawangan Johor in Johor Bahru, Malaysia. He holds a Master of Science in Chemistry and has contributed to the field of analytical chemistry, with a particular focus on forensic science, food chemistry, and environmental chemistry. His published work includes a study on the qualitative and quantitative analysis for determination of glue sniffer's urine. With 14 publications, 30 citations, an h-index of 3, and an i10-index of 1, he has established a solid foundation in his research areas. He also serves as a reviewer for the Global Journal of Science Frontier Research (GJSFR), reflecting his ongoing engagement with the scientific community.

References

Hippuric Acid - Wikipedia the free encyclopedia.

A. Serap, O. Pembe, K. Yusuf, K. Huseyin, E. Suheyla (2001) Medicolegal Aspects of Blood-Urine Toluene and Urinary Ortho-Cresol concentration in Toluene Exposure. 31, 415-419.

A. Arif (1988) E.; and Navaratnam, V., eds Abuse of Volatile Solvents and Inhalants: Papers Presented at a WHO Advisory Meeting International Monograph Series No 1. 1, 16-23.

M. Sharifah (1990) Report on the Inhalant Abuse Problem in Sarawak, East Malaysia. 12-16.

Jasmine S (2005) Powerless to act on glue sniffing.

Inhalant Wikipedia, the encyclopedia.htm Electrochemical behaviour of electrodeposited Ni- WC composite coatings.

International Programme on Chemical Safety (IPCS) (1986) IPCS International Programme on Chemical Safety Environmental Health Criteria 46.

WHO Regional Office for Europe (2000) Air quality guidelines for Europe.

(2004) Contaminants in soil: Collation of toxicological data and intake values for humans.

Carrie Anderson, M., Glenn Loomis, M. Recognition and Prevention of Inhalant Abuse.

K. Yamazaki, E. Tanaka, S. Misawa (1992) Urinary ortho-cresol concentrations as an indicator of toluene inhalation in glue-sniffers. 32(3), 215-223. https://doi.org/10.1016/s0015-7368(92)73074-6

George Gaffney, Kurt Schreier, Nicola Diferrante, Kurt Altman (1954) THE QUANTITATIVE DETERMINATION OF HIPPURIC ACID. 206(2), 695-698. https://doi.org/10.1016/s0021-9258(19)50838-9

Charles Umberger, Frank Fiorese (1960) Colorimetric Method for Hippuric Acid. 9(1), 91-96. https://doi.org/10.1093/clinchem/9.1.91

Y. Manabu, A. Atsushi, M. Tomoaki, W. Toshimitsu (2005) Simple colorimetric semiquantitation method of hippuri acid in urine for demonstration of toluene abuse. 7, 198-200.

Qualitative and Quantitative Analysis for Determination of Glue Snifferas Urine

Published

2014-04-22

How to Cite

Qualitative and Quantitative Analysis for Determination of Glue Snifferas Urine. (2014). Global Journal of Science Frontier Research, 14(15), 23-28. https://journalofscience.org/index.php/GJSFR/article/view/