Abstract

the present study was undertaken to investigate immunomodulatory activity of Clitoria ternatea seed and root extracts. Effects on humoral immune response were investigated in SRBCs-sensitized rats. Effects on cell medicated immunity were studied by measuring delayed type hypersensitivity (DTH) response in SRBC-sensitized rats. Neutrophil recruiting and phagocytosis were measured by studying neutrophil adhesion and carbon clearance method respectively. Further the effects on hematological parameters were also studied. C. ternatea seed and root extracts showed significant immunosupressive effects as evident from significant decrease in primary and secondary antibody titers in SRBCs-sensitized rats, paw thickness in DTH response, and neutrophil adhesion and In vitro Phagocytosis. The immunomodulatory effects of C. ternatea on humoral, cell mediated and non-specific immune response could be attributed to decreased immune cell sensitization, immune cell presentation and phagocytosis. The anti-inflammatory and antioxidant properties of plant might be playing major role in immunomodulatory activity. The present study provided evidence for the traditional uses of the plants in Indian system of medicine.

How to Cite
SOLANKI, Yogendrasinh B.; M. JAIN, Sunita. Immunomodulatory Activity of Ayurvedic Plant Aparajita (Clitoria Ternatea L.) In Male Albino Rats. Global Journal of Science Frontier Research, [S.l.], v. 10, n. 3, july 2010. Available at: <https://journalofscience.org/index.php/GJSFR/article/view/19>. Date accessed: 15 aug. 2018.